Figure 1.

Domain organization and composition of chromatin-remodeling complex. (A) Domain organization of four chromatin remodeler complexes. Remodelers can be divided into four subfamilies according to the domain organization in the catalytic ATPases and their associated subunits. The ATPase domains in all of the remodelers are used to mobilize nucleosomes and comprise two RecA-like folds, which are separated by an insertion (yellow). Asterisk represents structural similarity. (B) The main complexes in each subfamily. The ATPase subunits, shared subunits, and variable subunits of the representative complexes in each of the four families of human chromatin remodelers.