Table 2.
Hexane reference limits and toxicological evaluation.
| Toxicological Assessment | Toxicity Indicators | Codes and Values | References |
|---|---|---|---|
| ECHA registration dossier a | Hazard statements | H225, H304, H315, H336, H361f, H373, H411 | [26] |
| Reference concentration for chronic inhalation exposure (general population) a | RfC (mg/m3) | 0.72 | [47] |
| Reference dose for chronic oral exposure (general population, oral, pharmaceutical residue) a | RfD (mg/kg body weight human/day) | Not assessed due to lack of data | [47] |
| Permitted daily exposure (general population) a | PDE (mg/day for an average human of 50 kg) | 2.9 | [50] |
| Indicative occupational exposure limit values a | IOELV for 8 h of exposure (mg/m3) | 72 | [51] |
| Maximum residue limits in the extracted foodstuff or food ingredient b | MRL in fat or oil or cocoa butter (mg/kg) | 1 | [9] |
| MRL in food containing defatted protein and defatted flours (mg/kg) | 10 | ||
| MRL in defatted soya products as sold to the final consumer (mg/kg) | 30 | ||
| MRL in foodstuff containing solvent-extracted flavourings from natural flavouring materials (mg/kg) | 1 | ||
| Maximum residue limit in animal feed materials b | MRL in feed materials (mg/kg) | 1000 | [52] |
an-hexane (CAS 110-54-3); b hexane (EC number 925-292-5).