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. Author manuscript; available in PMC: 2023 Apr 30.
Published in final edited form as: Toxicology. 2022 Apr 19;472:153189. doi: 10.1016/j.tox.2022.153189

Figure 1.

Figure 1.

Diazinon effects on locomotor activity and its habituation in the Figure-8 apparatus (mean ± sem). (A) Locomotor activity at 5 months of age. (B) Locomotor activity at 1 year of age. (C) Linear habituation function for 5 month old rats. (D) Linear habituation function for 1 year old rats. The higher 1.0 mg/kg/day DZN dose caused significant hypoactivity relative to controls during the blocks 12 (p < 0.05) at 5 months of age and hyperactivity in block 4 (p < 0.05) at 1 year of age. 5 month old rats with 1.0mg/kg/day DZN exposure showed higher intercepts and steeper habituation slopes than controls in the linear analysis. No linear differences were detected in middle-aged adults.