Effects of DZN exposure on DA and DOPAC levels and DOPAC/DA ratio (turnover): (A) DA in striatum, (B) DOPAC in striatum, (C) DOPAC/DA in striatum, (D) DA in frontal/parietal cortex, (E) DOPAC in frontal/parietal cortex, (F) DOPAC/DA in frontal/parietal cortex. Assessments were made on at PN150 (5 months of age) and at ~PN450 (15 months age). Data represent mean ± SE obtained from 7–17 animals in each treatment group at each age. Where significant differences were found, posthoc Tukey tests were used to establish specific intergroup differences (brackets and asterisks). NS = not significant.