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. 2022 Nov 1;27(21):7426. doi: 10.3390/molecules27217426

Figure 3.

Figure 3

The proposed binding mechanism between the CA II isoenzyme and 4-bromo-5-(4-bromo-2,5-dihydroxybenzyl)benzene-1,2-diol (20) by anchoring to the zinc ion (Zn2+) coordinated water (H2O)/hydroxide ion (-OH).