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. 2022 Oct 31;14(21):5361. doi: 10.3390/cancers14215361

Table 1.

Clinicopathological feature.

Variables Learning Set (2011–2015) Validation Set (2016–2017)
n = 91 n = 49
Age, median (years) * 66 (41–86) 66 (35–84)
Sex (male/female) 59/32 28/21
Location (colon/rectum) 54/37 32/17
Greatest diameter, median (mm) 20 (0–50) 20 (6–66)
Preoperative CEA (≥5/5</NA) (ng/mL) 12/78/1 11/36/2
Preoperative CA19-9 (≥38/38</NA) (ng/mL) 5/85/1 3/44/2
Degree of differentiation (tub1/tub2/others) 57/30/4 29/19/1
Depth of invasion, median (µm) * 2000 (0–9000) 2200 (91–12,000)
Lymph node metastasis (+/−) 7/84 7/42
Lymphatic invasion (+/−) 24/67 16/33
Vascular invasion (+/−) 12/79 7/42
Budding grade (1/2, 3/NA) 54/16/21 37/8/4

* Continuous variables were evaluated. CEA, Carcinoembryonic antigen; CA19-9, Carbohydrate antigen 19-9; tub, Tubular adenocarcinoma; NA, Not applicable.