Table 1.
Ketamine-Treated Sample (n = 16) | Case-Control Sample (n = 16) | |||
---|---|---|---|---|
Race, n (%) | ||||
White | 13 | (81.3%) | 13 | (81.3%) |
Black | 3 | (18.8%) | 2 | (12.5%) |
Unknown | -- | 1 | (6.3%) | |
Gender, n (%) | ||||
Female | 8 | (50%) | 8 | (50%) |
Male | 7 | (43.8%) | 7 | (43.8%) |
Transgender (female-to-male) | 1 | (6.3%) | 1 | (6.3%) |
Age, mean (SD) | 34.06 | (16.06) | 35.56 | (16.46) |
Taking psychotropic medication at time of index SA, n (%) | 15 | (93.8%) | 14 | (87.5%) |
Number of psychotropic medications, mean (SD) | 2.67 | (1.59) | 2.64 | (1.39) |
Principal diagnoses, n (%) ¥ | ||||
Unipolar | ||||
Major Depressive Disorder | 5 | (31.3%) | 2 | (12.5%) |
Major Depressive Disorder w/Psychotic Features | 2 | (12.5%) | 0 | (0%) |
Depressive Disorder NOS | 2 | (12.5%) | 7 | (43.8%) |
Bipolar | ||||
Bipolar I Disorder | 4 | (25%) | 2 | (12.5%) |
Bipolar I Disorder w/Psychotic Features | 1 | (6.3%) | 1 | (6.3%) |
Bipolar II Disorder | 2 | (12.5%) | 2 | (12.5%) |
Other Bipolar and Related | 0 | (0%) | 2 | (12.5%) |
Comorbid alcohol- or substance-use disorder, n (%) | 5 | (31.3%) | 2 | (12.5%) |
Note: No variables in the table above differed as a function of group (ketamine-treated vs. case–control patients) according to unpaired t-tests (for continuous variables) or Chi-squared tests (for categorical variables) (p’s > 0.19). ¥ Established by the Mini International Neuropsychiatric Interview for ketamine patients and the Electronic Medical Record review for case–control patients; this led to an increased prevalence of non-specific diagnoses (Depressive Disorder NOS; Other Bipolar and Related) in case–control patients who were not given a structured interview to clarify diagnosis. Groups were matched on the presence of unipolar vs. bipolar forms of depression at baseline.