Serum levels of NETosis and inflammatory biomarkers in recipients without CPB/ECMO (A–F) (n = 27) or with CPB/ECMO (G–L) (n = 9). Donors (n = 25) and recipients’ (n = 36) pre-, intra- and postoperative serum levels of NETosis (A–C,G–I) and inflammatory (D–F,J–L) biomarkers are displayed. Blue lines show biomarkers in non-PGD3 recipients and red lines in PGD3 recipients (Mixed-method analyses). The 95% confidence intervals are represented with bars. p values represent the global inter-group comparisons over time. Significant time-point differences are illustrated with asterisks (*). ** p < 0.01, *** p < 0.001, **** p < 0.0001.