. 2022 Oct 31;23(21):13233. doi: 10.3390/ijms232113233

Table 1.

E_max (mN/g) and EC₅₀ (μM) values of smooth muscle contraction induced by ACh application in the ileum, proximal colon, middle colon and distal colon of control (CTRL, n = 6–7) and streptozotocin-induced diabetic rats (STZ, n = 10).

	Ileum	Proximal Colon	Middle Colon	Distal Colon
Control
E_max (mN/g)	165.9 [116.4–216.0]	141.0 [116.7–278.5]	184.7 [68.95–378.8]	313.4 [176.2–823.1]
EC₅₀ (μM)	0.85 [0.32–3.53]	1.15 [0.22–14.70]	3.41 [1.1–4.8]	2.74 [0.94–7.47]
STZ
E_max (mN/g)	79.06 [34.65–338.9]	158.0 [75.0–569.5]	143.6 [86.56–411.3]	271.7 [163.6–370.9]
EC₅₀ (μM)	0.82 [0.27–1.87]	114.0 [8.31–3408]	18.96 [0.87–75.7]	2.94 [0.28–142.0]

For comparison between the two experimental groups (CTRL and STZ) we used a Mann–Whitney test. Values are median (95% confidence limits).