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. 2022 Nov 3;23(21):13464. doi: 10.3390/ijms232113464

Figure 11.

Figure 11

Proliferation and extracellular elastin content in primary cultures of aortic VSMCs from male or female Eln+/+ or Eln+/- mice. VSMCs were treated with SEP (0, 5, 10 or 50 µg/mL) for 1, 3 or 6 days. (A) Impact of SEP treatment on VSMC proliferation, evaluated by using the MTT assay. The results are expressed as percent of the control value (0 µg/mL SEP) of the same day. (B) Impact of SEP treatment on extracellular elastin content, evaluated by using an ELISA assay. The results are expressed as percent of the control value (0 mg/mL SEP) of the same day. * significant difference with same day control (three-way ANOVA, followed by LSD test for paired comparisons, p ≤ 0.05). $ significant difference at day 1 with same day control (two-way ANOVA, followed by LSD test for paired comparisons, p ≤ 0.05). Values are mean ± SEM. n = 3–5 primary cultures from separate animals in each group.