Table 1.
Basic Characteristics of Participants
| Variables | Simple T2DM (N=358) | Macrovascular Complications of T2DM (N=500) | P |
|---|---|---|---|
| Age, years | 68 (59,76) | 70(61,75) | 0.164 |
| Male, n% | 192 (53.6%) | 286 (57.2%) | 0.299 |
| Duration of diabetes, years | 5 (2,10) | 8 (5,12) | <0.001 |
| BMI,kg/m2 | 23.58(21.40,25.63) | 24.52(22.32,26.36) | <0.001 |
| WBC,109/L | 6.30 (5.10,7.60) | 6.80 (5.50,8.65) | <0.001 |
| RBC,1012/L | 4.39 (3.88,4.78) | 4.14 (3.63,4.54) | <0.001 |
| Neutrophils,109/L | 3.80 (2.90,4.90) | 4.50 (3.40,6.40) | <0.001 |
| ALT, U/L | 18.00 (12.50,29.53) | 16.45 (12.00,26.30) | 0.127 |
| AST, U/L | 18.00 (14.95,24.93) | 19.00 (15.00,27.00) | 0.180 |
| Albumin, g/L | 40.55 (37.3,43.3) | 39.4 (36.60,42.50) | 0.004 |
| SCr,μmol/L | 67.70 (55.70,83.70) | 77.70 (64.20,109.40) | <0.001 |
| BUN, mmol/L | 5.65 (4.60,7.23) | 6.63 (5.13,9.20) | <0.001 |
| FPG, mmol/L | 7.30 (6.11,9.23) | 8.47 (6.77,10.32) | <0.001 |
| TG mmol/L | 1.27 (0.90,1.78) | 1.79 (1.24,2.53) | <0.001 |
| TC, mmol/L | 4.58 (3.60,5.27) | 4.50 (3.63,5.35) | 0.818 |
| HDL-C, mmol/L | 2.64 (2.04,3.32) | 2.46 (1.85,3.03) | 0.001 |
| INR | 0.98 (0.91,1.12) | 0.99 (0.92,1.13) | 0.318 |
| TyG Index | 8.91±6.17 | 9.44±0.74 | <0.001 |
| Hypertension, n% | 176 (49.2%) | 376 (75.2%) | <0.001 |
| Medication history | |||
| ACEI/ARB, n% | 212(59.2%) | 217(43.4%) | <0.001 |
| Statins, n% | 276(77.1%) | 374(74.8%) | 0.439 |
| Metformin, n% | 70(19.6%) | 124(24.8%) | 0.07 |
| Alpha-glucosidase inhibitor, n% | 74(20.7%) | 127(25.4%) | 0.107 |
| Sulfonylurea, n% | 66(18.4%) | 86(17.2%) | 0.64 |
| Dipeptidyl peptidase 4 inhibitor, n% | 20(5.6%) | 17(3.4%) | 0.12 |
| Insulin, n% | 80(22.3%) | 142(28.4%) | 0.046 |
| Aortic calcification, n% | 123(14.3%) | 325(37.9%) | <0.001 |
Note: Data are presented as median (IQR) [25th percentile, 75th percentile] or n (%).
Abbreviations: BMI, body mass index; WBC, white blood cell count; RBC, red blood cell count, ALT, alanine aminotransferase; AST, aspartate aminotransferase; Scr, blood creatinine; BUN, blood urea nitrogen; FPG, fasting blood glucose; TG, triglyceride; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; INR, international normalized ratio; TyG Index, triglyceride glucose index; ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin-converting enzyme inhibitors.