Table 5.
Cox Proportional Hazards for All-Cause Mortality in T2DM with or without Macrovascular Complications
| Variables | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Age, years | - | - | 1.15(1.10–1.20) | <0.001 | 1.14(1.10–1.19) | <0.001 |
| Duration of diabetes, years | - | - | 1.01(0.97–1.05) | 0.652 | 1.01(0.97–1.06) | 0.636 |
| Aortic calcification | - | - | 0.93(0.51–1.71) | 0.811 | 0.85(0.46–1.58) | 0.603 |
| Hypertension | - | - | - | - | 0.79(0.44–1.42) | 0.430 |
| ACEI/ARB | - | - | - | - | 0.52(0.29–0.94) | 0.029 |
| Insulin | - | - | - | - | 1.47(0.83–2.61) | 0.188 |
| Albumin, g/L | - | - | - | - | 0.97(0.92–1.02) | 0.198 |
| SCr,μmol/L | - | - | - | - | 1.00(0.99–1.00) | 0.188 |
| BUN, mmol/L | - | - | - | - | 1.05(0.99–1.10) | 0.080 |
| TyG index | 1.87(1.32–2.64) | <0.001 | 1.99(1.38–2.86) | <0.001 | 1.89(1.29–2.76) | 0.001 |
Notes: Model 1 was unadjusted; Model 2 was adjusted for age, duration of diabetes, and aortic calcification; Model 3 was adjusted for age, duration of diabetes, aortic calcification, hypertension, history of ACEI/ARB medication, history of insulin medication, albumin, BUN, and SCr.
Abbreviations: Scr, blood creatinine; TyG Index, triglyceride glucose index; BUN, blood urea nitrogen; ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin-converting enzyme inhibitors; HR, hazard ratio; CI, confidence interval.