Table 1.

Antibacterial silver-based MOFs and their composition on the bacterial strain and antibacterial mechanism.

No.	Composition	Organic Ligands	Bacterial Strain	Test Value	Antibacterial Mechanism	Ref.
Pure Ag-MOFs
1	Ag6(m-O3PC6H4CO2)2	m-Phosphonobenzoic acid	S. aureus P. aeruginosa	MBC = 50–70 µM MBC = 20–30 µM	The consequent release of silver ions.	[98]
2	[Ag2(Cedcp)]n	N-(carboxyethyl)-(3,5-dicarboxyl)-Pyridinium bromide	E. coli S. aureus	MIC >37.84 µM MIC = 37.84 µM	1: The synergistic effect of the aromatic ring and pyridine. 2:The release of Ag+.	[99]
3	[Ag2(μ3-PTA)2(μ2-chdc)]n·5nH2O	1,3,5-triaza-7-Phosphaadamantane	S. aureus E. coli P. aeruginosa	MIC = 10 µg mL−1 MIC = 7 µg mL−1 MIC = 6 µg mL−1	The release of Ag+.	[100]
4	[Ag2(μ4-PTA)(μ4-mal)]n	1,3,5-triaza-7-Phosphaadamantane	E. coli P. aeruginosa S. aureus	MIC = 7 µg mL−1 MIC = 6 µg mL−1 MIC = 8 µg mL−1	The weak binding tendency of O and N donor atoms toward the center helps the slow release of Ag(I).	[101]
5	[Ag4(µ-PTA)2(µ3-PTA)2(µ4-pma)(H2O)2]n·6nH2O	1,3,5-triaza-7-Phosphaadamantane	E. coli P. aeruginosa S. aureus	MIC = 5 µg mL−1 MIC = 5 µg mL−1 MIC = 8 µg mL−1	Bond strengthens between Ag(I) and the ligand donor atoms and the Ag+ release.	[102]
6	[Ag(u3-PTA=S)] n(NO3) n·nH2O	1,3,5-triaza-7-Phosphaadamantane-7-sulfide	E. coli P. aeruginosa	MIC = 4 µg mL−1 MIC = 5 µg mL−1	Presence of silver nodes.	[103]
7	[Ag4(u4-PTA=S)(u5-PTA=S)(u2-SO4)2(H2O)2]n·2nH2O	1,3,5-triaza-7-Phosphaadamantane-7-sulfide	E. coli S. aureus	MIC = 20 µg mL−1 MIC = 40 µg mL−1	Presence of silver nodes.	[103]
8	Ag5(PYDC)2(OH)	Pyridine-3, 5-dicarboxylic acid	E. coli S. aureus	MIC = 10–15 ppm MIC = 15–20 ppm	1: The Ag+ interacts with bacteria. 2: The damage to the cell membrane.	[104]
9	[Ag2(O-IPA)(H2O)·(H 3O)]	5-Hydroxyisophthalic acid	E. coli	MIC = 5 µg mL−1 ZOI = 11.12 mm	Fastest Ag+ release rate and highest equilibrium concentration.	[104]
10	[AgL]n·nH2O	4-Cyanobenzoate	S. mutans F. nucleatum P. gingivalis	GIB = 5.29 ppm GIB = 5.29 ppm GIB = 5.29 ppm	Sustained-release of Ag+.	[105]
11	Ag (NDI-1)0.5(H2O)	Naphthalenediimide	E. coli S. aureus	IR = 100% IR = 99.52%	The synergistic reaction of the organic radical and the silver cation.	[106]
12	Ag7(NDI-2)1.5(CH3S)4(DMSO)3(DMSO)	Naphthalenediimide	E. coli S. aureus	IR = 99.96% IR = 100%	The synergistic reaction of the organic radical and the silver cation.	[106]
Hybrid Ag-MOFs
13	PLT@ Ag-MOF-Vanc	2-Methylimidazole	MRSA	MIC = 0.5 µg mL−1	1: Interfering with the intracellular metabolism of bacteria. 2: Catalytic production of the ROS. 3: Damage to the cell membrane integrity.	[111]
14	Ag-MOF @TFN	2-Aminoterephthalic acid	E. coli	MR = 90–96%	The release of Ag+.	[112]
15	Ag-MOF/TFC	2-Aminoterephthalic acid	P. aeruginosa	MR ~100%	The release of Ag+.	[113]
16	PVA/Ag-MOF @CS		S. aureus E. coli	ZOI = 12.1 mm ZOI = 9.7 mm	The release of Ag+.	[114]
17	CQDs @Ag-MOF	1,3,5-Benzenetricarboxylic acid	E. coli	MIC= 4 µg mL−1	1: Nanocomposite interactions with the cell membrane. 2: Degradation of the composite material. 3: The release of Ag+.	[115]
18	{[Ag6(μ3-HMNA)4(μ3-MNA)2]2−·[(Et3NH)+]2·(DMSO)2·(H2O)}	2-Thio-nicotinic acid	P. aeruginosa S. epidermidis S. aureus	ZOI = 14.0 ± 1.1 mm ZOI = 11.3 ± 1.3 mm ZOI = 11.8 ± 1.8 mm		[116]
19	GO−Ag-MOF TFN	1,3,5-Benzenetricarboxylic	E. coli	ER: 95%	The synergistic effect of the release of Ag + and the GO.	[117]
20	GO-Ag-MOF	1,3,5-Benzenetricarboxylic	E. coli B. subtilis	MIC = 50 ppm MIC = 50 ppm	The ROS of the GO damages the bacteria. The release of Ag+.	[117]
21	CS/SS/Ag- MOF–GO	1,3,5-Benzenetricarboxylic	S. aureus E. coli		Synergistic effect of the composite GO and the continuously released Ag.	[121]
22	P-CS @Ag-MOF	Pyridine-3, 5-dicarboxylic acid	S. aureus E. Coli	ZOI = 7.82 mm ZOI = 4.32 mm	1: The disruption of cells. 2: Ag(I)interaction with thiol proteins. 3: The combination between the bacterial cell cations and the organic linkers. 4: The release of the ROS.	[122]
23	P-CS @Ag- MOF	Pyridine-3, 5-dicarboxylic acid	S. aureus E. Coli	ZOI = 4.45 mm ZOI = 3.76 mm	1: The disruption of cells. 2: Ag(I) interaction with thiol proteins. 3: The combination between the bacterial cell cations and the organic linkers. 4: The release of the ROS.	[122]
Silver-containing polymer @MOFs
24	SD@Ag@CD-MOF	Cyclodextrin	E. coli S. aureus	MIC = 4 µg mL−1 MIC = 4 µg mL−1	The synergistic activity of the releasing Ag+ ions and SD.	[124]
25	Ag-Phy@ZIF-8@HA	2-Methylimidazole	S. aureus E. Coli	MIC = 0.13 µg mL−1 MIC = 0.25 µg mL−1	The synergistic activity of ZIF-8, Ag +, and Phy.	[125]
26	Ag-GOD@ ZIF-HA	2-Methylimidazole	E. Coli S. aureus	MIC = 39.7 µg mL−1 MIC = 79.3 µg mL−1	Synergetic effect of the release of Ag+ and GOD.	[126]
27	Ag-NPs@Ni-MOFs	Di-topic carboxylate	E. Coli P. aeruginosa	MIC = 0.025 ìg/mL MIC = 0.025 ìg/mL	Synergetic effect of the release of Ag+ and Ni-MOF.	[81]
28	Poly Cu-MOF@ Ag	Poly(terephthalic acid)	E. coli S. aureus	MIC = 2–5 µg mL−1 MIC = 10 µg mL−1	1: Release of Ag+ and Cu2+. 2: Generation of the ROS.	[127]
29	Ag-MIL-101(Cr)	Ditopic terephthalic acid	E. coli P. aeruginosaand S. aureus	MIC = 1ug mL−1 MIC = 1ug mL−1 MIC = 1ug mL−1	The release of smaller-sized Ag+ ions.	[128]
30	Ag@MOF-5	1,4-Benzenedicar-boxylic acid	E. Coli S. aureus	ZOI = 16.05 mm ZOI = 14.62 mm	1: Silver ions hinder the bacterial DNA replication. 2: Nano-silver destroys the cell membrane. 3: Produces the ROS of	[129]
31	Ag@Mg-MOF-PVDF	Sebacic acid	S. aureus	ZOI = 10 mm	the release of Ag+.	[130]
32	Ag/Zn-MOF	2-Aminoterephthalic acid	E. coli S. aureus	ZOI= 11 mm ZOI= 12 mm	1: Slow release of the silver ions. 2: Ag+ interacts with the S, O, and N atoms.	[131]
33	GS5-CL-Ag@CD-MOF	Cyclodextrin	E. Coli S. aureus	MIC = 16 µg mL−1 MIC = 64 µg mL−1	The Ag NPs released.	[127]
34	MN-MOF-GO-Ag	Gallic acid	S. aureus E. coli P. aeruginosa		The synergistic reaction of the GO and Ag.	[128]