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. 2022 Oct 28;23(21):13130. doi: 10.3390/ijms232113130

Figure 6.

Figure 6

BPF suppresses CLP-induced cytokine production of peritoneal macrophages and improves the mortality of CLP mice. (A–C) CLP-operated mice were injected with DMSO or BPF (0.09, 0.22, or 0.44 mg/kg, intravenous injection). After 12 h, the mice were euthanized. Peritoneal macrophages were collected from CLP-operated mice and the levels of the indicated inflammatory cytokines were determined using ELISA (n = 5). All results are shown as means ± SD of three different experiments with triple samples. * p < 0.1 compared to CLP only; (D) CLP surgery was conducted on mice and the indicated reagents were administered every 24 h (n = 20). The survival of mice was monitored for 96 h. * p < 0.5.