Skip to main content
. 2022 Nov 5;23(21):13587. doi: 10.3390/ijms232113587

Figure 6.

Figure 6

Validation of predicted target genes of miR-381 using dual luciferase reporter assay. (A) The binding sequences of miR-381 with the 3′UTR of JAG2 and PTEN in wild-type dual luciferase reporter vectors. (B) The complementary sequences of the binding sequences in mutant-type dual luciferase reporter vectors. (C,D) The luciferase activities of the target genes JAG2 and PTEN for miR-381 detected by dual luciferase reporter assay. (E,F) The effect of miR-381 on the expression levels of JAG2 and PTEN. * p < 0.05 and ** p < 0.01.