ADC	Antibody drug conjugate
AntiSMASH	Antibiotics and secondary metabolite analysis shell
BAC	Bacterial artificial chromosome
BGC	Biosynthetic gene cluster
CATCH	Cas9-assisted targeting of chromosome segment
CRISPR-Cas	clustered regularly interspaced short palindromic repeats-CRISPR associated protein
DCas	Dead Cas
DSB	Double-strand break
E. coli	Escherichia coli
sNCBI	National center for biotechnology information
NP	Natural product
NRPS	Nonribosomal peptide synthetase
PKS	Polyketide synthase
RiPPs	Ribosomally synthesized and posttranslationally modified peptides
S. cerevisiae	Saccharomyces cerevisiae
TAR	Transformation-associated recombination
U.S. FDA	United States Food and Drug Administration