Figure 1.

Antibiofilm activity of PomeGr. C. albicans (10⁶/mL) was exposed to PomeGr or neg-C at the indicated dilutions, and incubated at 37 °C for 24 h; then, after removing planktonic cells, biofilm was quantified. Upper panel: 24 h-biofilm formation by Candida exposed to Pomegr (grey bars) or negative control (white bars), assessed by CV assay. The black bar represents the biofilm production by C. albicans in medium only. Central panel: percentage of biofilm formation by C. albicans exposed to PomeGr, evaluated by fluorescence assay. Lower panel: percentage of biofilm formation by C. albicans exposed to PomeGr, as evaluated by CV assay. The data are the means ± SEM of nine replicates of three independent experiments. The asterisks indicate statistically significant differences: * p < 0.05 (PomeGr-treated vs. neg-C samples).