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. 2022 Oct 22;14(21):5173. doi: 10.3390/cancers14215173

Table 2.

Adverse events experienced by patients while receiving cabozantinib.

Adverse Event Any Grade
N (%)
Grade 3 or 4
N (%)
Fatigue 13 (50) 0 (0)
Anorexia 9 (35) 1 (4)
AST elevation 9 (35) 0 (0)
Diarrhea 8 (31) 1 (4)
Hypertension 7 (27) 1 (4)
Abdominal discomfort 6 (23) 0 (0)
Dyspepsia 6 (23) 0 (0)
ALT elevation 6 (23) 0 (0)
Stomatitis 4 (15) 1 (4)
Weight loss 4 (15) 0 (0)
Rash 4 (15) 0 (0)
Peripheral edema 4 (15) 0 (0)
Constipation 3 (12) 0 (0)
Low Platelets 2 (8) 1 (4)
Dyspnea 2 (8) 0 (0)
Bowel obstruction 1 (4) 1 (4)
Palmar-Plantar erythrodysesthesia 1 (4) 1 (4)
Rectal abscess 1 (4) 1 (4)
Dry Skin 1 (4) 0 (0)
Hair loss 1 (4) 0 (0)
Dysgeusia 1 (4) 0 (0)
Headache 1 (4) 0 (0)
Back Pain 1 (4) 0 (0)
Insomnia 1 (4) 0 (0)
Flatulence 1 (4) 0 (0)
Confusion 1 (4) 0 (0)
Bilirubin elevation 1 (4) 0 (0)
Anemia 1 (4) 0 (0)