Table 2.

Cell Populations Percentages of Variable irAE Severity.

Cell Type	Healthy Control	irAE 0	irAE 1	irAE 3	Log Fold Change (Healthy–0)	Log Fold Change (0–1)	Log Fold Change (1–3)
Naïve B	2.865	11.60	7.915	6.196	2.02	−0.55	−0.35
CD14+ Monocyte	14.93	21.48	43.09	30.07	0.52	1.00	−0.52
CD16+ Monocyte	1.684	11.72	8.040	15.06	2.80	−0.54	0.91
CD4+ T Central Memory	35.32	26.59	21.98	26.54	−0.41	−0.27	0.27
CD8+ T Effector Memory	12.55	0.3927	0.1256	0.1270	−5.00	−1.64	0.02
Natural Killer Cell	3.057	23.72	18.22	14.02	2.96	−0.38	−0.38

Avg Predictive Score is a composite average of the mean predictive strength of the cell identification made for each cell type taken across all three cell populations.