5hmC	5-hydroxymethylcytosine	LTP	Long-term potentiation
5mC	5-methylcytosine	MBD	Methyl-CpG-binding domain
AD	Alzheimer’s disease	mCA	Methylated CA
ADK	Adenosine kinase	mCAC	Methylated CAC
ADO	Adenosine	mCG	Methylated CpG
ADORA2A	Adenosine A2a receptor	MCI	Mild cognitive impairment
AHCY	Adenosylhomocysteinase	Met	Methionine
ALS	Amyotrophic lateral sclerosis	mGluRI	Metabotropic glutamate receptor group I
AMP	Adenosine monophosphate	mHTT	Mutant HTT
ASD	Autism spectrum disorders	mQTL	Methylation quantitative trait locus
Aβ	Amyloid beta	MTs	Microtubules
C9orf72	Chromosome 9 open reading frame 72	NCI	No cognitive impairment;
D-loop	Displacement loop	NFT	Neurofibrillary tangles
DMRs	Differentially methylated regions	NPCs	Neural progenitor cells
DNAm	DNA methylation	NTD	N-terminal domain
DNMTs	DNA methyltransferases	PB	Peripheral blood
DRPs	Dipeptide repeat proteins	PBMCs	Peripheral blood mononuclear cells
FMRP	Fragile X mental retardation protein	PHFs	Paired helical filaments
FTD	Frontotemporal dementia	pHRE	Pathogenic hexanucleotide G4C2 repeats expansion
FXS	Fragile X syndrome	Pol II	RNA polymerase II
G4C2	GGGGCC	p-tau	Phosphorylated-tau
GABA	Gamma-aminobutyric acid	RAN	Repeat-associated non-ATG translation
GoF	Gain of function	RBPs	RNA binding proteins
Hcy	Homocysteine	SAH	S-adenosyl homocysteine
HD	Huntington’s disease	SAM	S-adenosyl methionine
HTT	Huntingtin gene	SNCA	α-synuclein
ICIs	Intracytoplasmic inclusions	SNP	Single-nucleotide polymorphism
INIs	Intranuclear inclusions	SZ	Schizophrenia
LAS	Lysosomal autophagy system	TET	Ten-eleven translocation
lncRNAs	Long non-coding RNAs	TFs	Transcription factors
LoF	Loss of function	TRD	Transcriptional repression domain
LTD	Long-term depression