Table 2.

miRNAs as biomarkers in HER2+ breast cancer.

miRNA	Reference	Value in HER2+ Breast Cancer
miR-451a, miR-16-5p, miR-17-3p, miR-940	Li H et al. (2018) [60]	Predictor of response and prognostic role
miR-27b, miR-433, miR-16, miR-328, miR-660, miR-422a	Stevic et al. (2018) [67]	Predictive role, association with N-status, distinction between TNBC and HER2+ BC
miR-21	Liu et al. (2019) [68]	Predictor of response
miR-222-3p	Zhang et al. (2020) [69]	Predictive and prognostic role and association with cardiotoxicity and anemia, side effects of trastuzumab therapy
miR-205	Cataldo et al. (2018) [72]	Predictor of response and prognostic role
miR-675, miR-204	Müller et al. (2019) [73]	Indicators of disease aggressiveness
miR-100-5p, miR-374a-5p, miR-574-3p, miR-140-5p, miR-328-3p, miR-145-5p, miR-34a-5p, miR-98-5p, miR-100-5p, miR-144-3p, miR-362-3p, miR-197-3p, miR-320c, miR-100-5p, miR-376c-3p, miR-874-3p,	Di Cosimo et al. (2019) [64]	Predictive and prognostic role
miR-148a-3p, miR-374a-5p	Di Cosimo et al. (2020) [65]	Predictive role
miR-215-5p, miR-30c-2-3p, miR-153-3p, miR-219a-5p, miR-31-3p, miR-382-3p	Pizzamiglio and Cosentino et al. (2021) [66]	Predictive and prognostic role