Table 2.
MicroRNA modulation and function in SGTs.
MicroRNA | SGC Subtype | Function | Levels 1 | References |
---|---|---|---|---|
hsa-let-7a | SGTs | Prognostic | + | [44,55] |
hsa-let7g | SGTs | Diagnostic | − | [46] |
hsa-let7g-5p | SGTs | Prognostic | − | [52,56] |
hsa-miR-100 | SGTs | Prognostic | − | [45,52] |
hsa-miR-103a-3p | PGT | Prognostic | + | [56] |
hsa-miR-106 | ACC | Prognostic | + | [44] |
hsa-miR-106a | SGTs | Prognostic | + | [52] |
hsa-miR-106b | SGTs | Prognostic | + | [52] |
hsa-miR-1180 | ACC | Prognostic | + | [57] |
hsa-miR-1233 | PGT | Diagnostic | + | [56] |
hsa-miR-125a-5p | ACC | Prognostic | + | [30] |
hsa-miR-125b | SGTs | Prognostic | − | [45,52] |
hsa-miR-1267 | PGT | Diagnostic | + | [56] |
hsa-mir-132 | AP ACC MEC | Prognostic | + | [48] |
hsa-miR-132 | PGT | Diagnostic | − | [46,48] |
hsa-miR-133b | SGTs | Prognostic | + | [54] |
hsa-miR-135a-5p | SGTs | Diagnostic | − | [52] |
hsa-miR-140 | SGTs | Prognostic | − | [46,52,55] |
hsa-miR-140-5p | PGT | Diagnostic | − | [46] |
hsa-miR-140-5p | SGTs | Prognostic | − | [46,52] |
hsa-miR-146b | SGTs | Diagnostic | + | [47] |
hsa-miR-150 | ACC | Prognostic | + | [44] |
hsa-miR-152 | ACC | Prognostic | + | [57] |
hsa-miR-15b | PGT | Diagnostic | − | [46] |
hsa-mir-16 | AP ACC MEC | Prognostic | + | [48] |
hsa-miR-17 | AP ACC MEC | Prognostic | + | [44,48] |
hsa-miR-17 | SGTs | Diagnostic | + | [48] |
hsa-mir-181a-2 | ACC | Prognostic | + | [57] |
hsa-miR-1825 | PGT | Diagnostic | + | [56] |
hsa-mir-195 | AP ACC MEC | Prognostic | − | [48] |
hsa-miR-195 | SGTs | Diagnostic | − | [52] |
hsa-miR-195-5p | SGTs | Diagnostic | − | [52] |
hsa-miR-199a | SGTs | Diagnostic | + | [47] |
hsa-miR-199a-5p | SGTs | Diagnostic | + | [52] |
hsa-miR-205 | MEC | Prognostic | + | [54] |
hsa-miR-20a | ACC | Prognostic | + | [44,52] |
hsa-mir-21 | ACC | Prognostic | + | [57] |
hsa-miR-21 | SGTs | Diagnostic | + | [47,52] |
hsa-miR-211 | PGT | Diagnostic | + | [56] |
hsa-miR-211-3p | ACC | Prognostic | − | [45] |
hsa-miR-22 | MEC | Prognostic | + | [54] |
hsa-mir-221 | AP ACC MEC | Prognostic | − | [48] |
hsa-miR-221 | AP ACC MEC | Diagnostic | − | [48] |
hsa-miR-222 | PGT | Diagnostic | − | [46] |
hsa-miR-222-3p | SGTs | Diagnostic | + | [52] |
hsa-miR-222-3p | SGTs | Prognostic | + | [46,52] |
hsa-miR-30e | SGTs | Diagnostic | + | [47] |
hsa-miR-31 | SGTs | Diagnostic | + | [47] |
hsa-miR-3125 | MEC | Prognostic | − | [54] |
hsa-miR-3131 | ACC | Prognostic | − | [45] |
hsa-miR-320a | ACC | Prognostic | + | [50] |
hsa-miR-320e | SGTs | Diagnostic | + | [52] |
hsa-miR-345 | SGTs | Diagnostic | + | [47] |
hsa-miR-374 | SGTs | Diagnostic | + | [56] |
hsa-miR-374 | SGTs | Prognostic | + | [46,52] |
hsa-miR-374c | ACC | Prognostic | + | [57] |
hsa-miR-375 | ACC | Prognostic | − | [44,45,52] |
hsa-miR-4430 | ACC | Prognostic | + | [45] |
hsa-miR-4487 | ACC | Prognostic | + | [45] |
hsa-miR-455-3p | ACC | Prognostic | + | [44] |
hsa-miR-4676 | ACC | Prognostic | + | [57] |
hsa-miR-4717-5p | ACC | Prognostic | + | [57] |
hsa-miR-486-3p | ACC | Prognostic | + | [45] |
hsa-miR-5191 | ACC | Prognostic | − | [45] |
hsa-miR-577 | PGT | Diagnostic | + | [46] |
hsa-miR-582-5p | MEC | Prognostic | − | [54] |
hsa-mir-6865 | ACC | Prognostic | + | [57] |
hsa-miR-9 | AP ACC MEC | Prognostic | − | [48] |
hsa-miR-9 | AP ACC MEC | Diagnostic | − | [48,52] |
hsa-miR-93 | SGTs | Prognostic | + | [52] |
hsa-miR-99a | SGTs | Prognostic | − | [45,52] |
hsa-miR-99b | SGTs | Prognostic | + | [55] |
1 Expression levels compared to healthy controls and/or benign tumors if the Diagnostic value is assigned. If the Prognostic value is assigned, the level increases (+) or decreases (−) with the cancer progression.