Table 2.

Peculiar clinical signs of MIS-C and the differential diagnosis with similar diseases.

	MIS-C	Kawasaki Disease	Hemophagocytic Lymphohis-Tiocytosis/Macrophage Activation Syndrome (HLH/MAS)	Toxic Shock Syndrome
Age of affected persons	4–15 years	<5years		<10 years
Ethnicity	Hispanic/Latino/African American	Est Asian	No difference	No difference
Symptoms
Hypotension	Present or absent	Generally absent	Generally absent	Present
Rash	Generally present	Generally present	Present or absent	Generally present
Fever	Present	Present	Present	Present
Vomiting/Diarrhea/or abdominal pain	Generally present	Rare	Present or absent	Generally present
Respiratory distress	Generally present	Rare	Generally present	Present
Myocarditis and pericarditis	Generally present	Rare	Present or absent	Rare
Hemodynamic instability	Present or absent	Rare	Present or absent	Present or absent
Coronary artery dilatation and aneu- rysms	Present or absent	Present	Generally absent	Generally absent
Heart involvement	Generally present	Present	Present or absent	Present or absent
Mucous Membrane Involvement	Present or absent	Generally present	Generally present	Rare