Figure 2.

Genes whose gain or loss of function significantly changes the percentages of type 1 (A), type 2A (B), or type 2X/B (C) fibres when compared to wildtype or control mice. Red symbols: loss-of-function; blue symbols: gain-of-function. ● Soleus; ⬣ extensor digitorum longus (EDL); ◆ plantaris; ◼ tibialis anterior; ▲ biceps femoris; ▼ quadriceps; and ◯ gastrocnemius. In (C), filled symbols refer to 2X muscle fibres and symbols without filling indicated 2B fibres. Note that the “◯”-marked data in (A,B) were reported as statistically significant even though they are close to “0” (i.e., no change).