Table 2.
Information on Reconstruction of 3D structures of TBEV proteins, the template strain SofjinKSY (AEP25267.2).
| Protein in the Strain SofjinKSY | Closely Related Atomic Structure from PDB | Similarity Degree between SofjinKSY and PDB Structure (%) | Structural Region Length (aa) | Coordinates of a Structural Region in SofjinKSY | Coordinates of a Structural Region in a Polyprotein |
|---|---|---|---|---|---|
| preM | 7qrf 1 | 96.88 | 79 | 6–84 | 118–196 |
| M | 7z51 2 | 88.00 | 74 | 94–167 | 206–279 |
| E | 7z51 | 95.36 | 494 | 1–494 | 281–774 |
| NS1 | 5gs6 3 | 42.12 | 351 | 2–352 | 778–1128 |
| NS2a | - 4 | - | - | - | - |
| NS2b | - | - | - | - | - |
| NS3 | 2whx 5 | 45.75 | 599 | 23–621 | 1512–2110 |
| NS4a | - | - | - | - | - |
| NS4b | - | - | - | - | - |
| NS5 | 4k6m 6 | 56.58 | 887 | 5–891 | 2516–3402 |
1 Structure of the dimeric complex between a precursor membrane ectodomain (prM) and an envelope protein ectodomain (E) of TBEV; 2 The small membrane protein (M) in a complex with the envelope protein (E) of TBEV; 3 The NS1 protein of Zika virus; 4 Dashes mean inability to reconstruct a 3D structure due to the absence of homologues in PDB; 5 A second conformation of the NS3 protease-helicase from dengue virus; 6 Crystal structure of the full-length Japanese encephalitis virus NS5 protein.