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Effect of MCC950 on different cytokines in the presence/absence of MnCl2. N2a cells were exposed to MnCl2 with/without MCC950 (0.1, 1 and 10 µM) detected by ELISA post 24 h. (a) TNFα, (b) IL-18, (c) IL-1β, (d) caspase-1. Data represent the mean ± SD, significance calculated with reference to +ve group, i.e., MnCl2 500 µM. *** p < 0.0001 vs. control group.
