Table 2.
Homing peptides used for the development of Peptide-drug-conjugates.
| Homing Peptide | Receptor Site [71,73,73,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93] |
|---|---|
| Somatostatin (SST) | Somatostatin receptor |
| Gonadotropin-releasing hormone (GnRH) | Receptor version of hormone-GnRH-R |
| Angiopep-2 | Low-density lipoprotein receptor-related protein (LRP-1) |
| Epidermal growth factor (EGF) | Epidermal growth factor receptor (EGFR): HER1, HER2, HER3, HER4 |
| REG | Integrin αvβ3 receptor |
| iREG | Integrin αvβ3/αvβ5 receptor |
| GE11 | Epidermal growth factor receptor (EGFR): ErbB1 |
| D-Lys6-LHRH | Luteinizing hormone-releasing hormone receptor (LHRH-R) |
| Octreotide | Somatostatin receptor 2/5 (SSTR2/5) |