Table 1.
Assessment of ability to inhibit lipid accumulation on HepG2 cells of candidate strains.
| Samples | Lipid Accumulation (% of Control) |
Percent Reduction (Compared with OA-C) |
|---|---|---|
| Control | 100 ± 1.12 | - |
| OA-C | 173.76 ± 7.18 #### | - |
| Simvastatin (1 µM) | 136.87 ± 5.23 ** | 21.23 |
| Lactobacillus gasseri MJM61024 | 122.59 ± 0.85 *** | 29.45 |
| Lactobacillus rhamnosus GG | 151.53 ± 2.12 ** | 12.79 |
| Lactobacillus rhamnosus MJM60370 | 157.33 ± 5.47 * | 8.93 |
| Lactobacillus brevis MJM60386 | 132.25 ± 1.23 ** | 23.89 |
| Lactobacillus heveticus MJM60419 | 158.27 ± 4.87 * | 8.91 |
| Lactobacillus fermentum MJM60430 | 172.69 ± 4.23 | 0.62 |
| Lactobacillus casei MJM60432 | 177.36 ± 5.06 | −2.07 |
| Lactobacillus paracasei MJM60434 | 152.72 ± 5.97 * | 12.11 |
| Lactobacilus helveticus MJM60463 | 160.42 ± 4.37 | 7.68 |
| Streptococus thermophilus MJM60636 | 171.11 ± 2.98 | 1.53 |
| Lactobacillus sakei MJM60958 | 92.46 ± 1.16 **** | 46.79 |
| Lactobacillus rhamnosus MJM60711 | 146.26 ± 3.19 ** | 15.83 |
| Lactobacilus helveticus MJM60825 | 152.72 ± 5.97 * | 12.11 |
| Lactobacillus plantarum MJM61025 | 145.53 ± 3.08 ** | 16.25 |
| Lactobacillus curvatus MJM61026 | 139.46 ± 3.39 ** | 19.74 |
OA-C: 1 nM oleic acid and 7.5 µg/mL cholesterol (negative control). #### p < 0.0001 compared with control; * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 compared with OA-C.