Skip to main content
. 2022 Nov 2;23(21):13394. doi: 10.3390/ijms232113394

Figure 1.

Figure 1

Effects of MTX (Methotrexate), CS12192, or the combination of CS12192 and MTX on the severity of CIA rats: (A) The representative hind paws of CIA rats from different experimental groups (the red arrows are red and swollen joints). (B) The arthritis scores of different groups were quantified throughout the experimental period; medians were compared using One-way ANOVA; * p < 0.05; ** p < 0.01; and *** p < 0.001. (C) The results of X-ray examination. (D) X-ray semiquantitative analysis results; each bar represents the mean ± SEM for 10 CIA rats in different groups; * p < 0.05; ** p < 0.01; and *** p < 0.001 as indicated.