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Mitogen-activated protein kinase signaling pathway modulating mediators of the skin aging process. AP-1, activator protein 1; Nrf2, nuclear factor (erythroid-derived 2)-like 2; NF-κB, Nuclear factor-kappa B; MMP, metalloproteinases; NQO11, NADPH-quinone oxidoreductase 1; HO-1, heme oxygenase-1. The illustration was drawn using Biorender software.
