Table 1.
Main isolated natural compounds with anti-aging effects by acting on skin elasticity and wrinkle formation.
| Compounds | Test | Effects | Refs |
|---|---|---|---|
| α-mangostin from Garcinia mangostana |
In vitro (keratinocytes) In vivo (hairless mice) |
Downregulation of UV-induced MMP-1/MMP-9 Reduction in UV-induced wrinkles |
[19] |
| Batatasin III from Dendrobium loddigesii | In vitro (fibroblasts) | Increase in collagen synthesis | [20] |
| Ferulic acid from several plant origin | Clinical trial | Enhancement of skin elasticity by bleaching, anti-redness, smoothing, and moisturizing activities | [25] |
| Jasmonate derivative | In vitro (keratinocytes) | Upregulation of proteoglycans Increase in glycosaminoglycan production |
[23] |
| Limonoids from Carapa guianensis |
In vitro (fibroblasts) | Increase in collagen synthesis | [21] |
| Polysaccharides from Panax ginseng | In vitro (keratinocytes) | Downregulated UV-induced MMP-1 expression | [24] |
| Triterpenoids from Eriobotrya japonica | In vitro (fibroblasts) | Increase in collagen synthesis | [22] |