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Inflammatory reaction in the KO vs. WT mice. (A). Immunolabeling of retinal astrocyte processes for GFAP and microglia for Iba1 in the ganglion cell layer of the retinal flat mounts showed infiltration by monocytes (the round Iba1 positive cells) in the ganglion cell layer. (B). Iba1 immunolabeling shows increased activated microglia cells in the photoreceptor outer segments layer. Scale bar: 20 µm. 10 WT and 10 KO mice were analyzed for each study. * p < 0.05, *** p < 0.001.
