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. 2022 Oct 22;23(21):12729. doi: 10.3390/ijms232112729

Figure 4.

Figure 4

Adiponectin inhibits NF-κB and STAT3 activation in NPC cells. Luciferase reporter assay of NF-κB (A) and STAT3 (B) in S18 and 5-8F cells after treatment with 40 μg/mL adiponectin for 3 h. (C) Western blot analysis of p-IκBα, cyto-p65, and nuc-p65 in S18 and 5-8F cells after treatment with various doses of adiponectinfor 6 h. (D) Western blot analysis of p-STAT3, cyto-STAT3, and nuc-STAT3 in S18 and 5-8F cells after treatment with various doses of adiponectin for 6 h. Results are presented as mean ± SD of three independent experiments performed in triplicate. ** p < 0.01, *** p < 0.001.