ABCA3	ATP Binding Cassette Subfamily A Member 3 protein coding gene
ALL	Acute lymphoblastic leukemia
AML	Acute myeloblastic leukemia
ANTP homeobox oncogenes	Antennapedia homeobox oncogenes
B-ALL	B-cell acute lymphoblastic leukemia
Bcl-2	B-cell lymphoma 2
BCP-ALL	B-cell progenitor acute lymphoblastic leukemia
BCR-ABL	BCR ABL fusion genes
BEX1	Brain Expressed X-Linked 1 protein coding gene
BFM therapy	Berlin-Frankfurt-Münster therapy
CASP8AP2	Caspase 8 associated protein 2
CDKN2A	Cyclin Dependent Kinase Inhibitor 2A
CGIs	CpG islands
CIMP	CpG Island Methylator Phenotype
CIMP	negative CGI methylator phenotype
CIMP+	positive CGI methylator phenotype
CIR3y	3-year cumulative incidence of relapse
CNS	Central nervous system;
COSMe	CpG island and Open Sea Methylation
COSMe-I	CpG island and Open Sea Methylation type I
COSMe-II	CpG island and Open Sea Methylation type II
CREBBP	CREB Binding Protein
CSF	Cerebrospinal fluid
DMR	Differentially methylated region
DNMT inhibitors	Inhibitors of DNA methyltransferases
DOT1L	Disruptor of telomeric silencing 1
EPZ-5676	Pinometostat
ETV6	ETS translocation variant gene 6
ETV6-RUNX	ETV6 RUNX fusion gene
FDA	Food and Drug Administration
H3K79me	Histone H3 lysine methylation
H4R3sme2	symmetric dimethylation of H4R3
HAT	histone acetyltransferase
HDAC	histone deacetylase
HDACi	HDAC Inhibitors
HMAs	Hypomethylating agents
Hyper-CVAD	Hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone
KMT2A	lysine methyltransferase 2A protein coding gene
MDS	Myelodysplastic syndromes
MiRNA	Micro RNA;
MLL	Mixed Lineage Leukaemia
MRD	Minimal Residual Disease
MYO18B	Myosin XVIIIB protein coding gene
NR3C1 protein	Nuclear Receptor Subfamily 3 Group C Member 1 protein
P2RY8-CRLF2	P2RY8-CRLF2 fusion gene
PCDH17	Protocadherin 17 protein coding gene
Ph+	Philadelphia chromosome positive
PLCB4	Phospholipase C Beta 4 protein coding gene
PLXND1	Plexin D1 protein coding gene
PRC2	Polycomb Repressor Complex 2
PRMT5	Protein arginine methyltransferase 5
SNP	Single Nucleotide Polymorphism
STIL-TAL1	STIL TAL1 fusion genes
TAL1	TAL BHLH Transcription Factor 1 coding gene
T-ALL	T-cell acute lymphoblastic leukemia
TCF3-PBX1	TCF3-PBX1 fusion gene
TET	Ten-eleven translocation
VEGF-A	Vascular endothelial growth factor A
WIF1	Wnt Inhibitory Factor 1