TABLE 1.
Reactivity of the NspA-specific MAbs with different strains of N. gonorrhoeae and N. meningitidis
| MAb | Isotypea | No. of strains recognized/total no. testedb
|
|
|---|---|---|---|
| N. gonorrhoeae | N. meningitidisc | ||
| 11E9 | IgG1 | 51/51 | 1/8 |
| 1D4 | IgG2a | 51/51 | 1/8 |
| 13E5 | IgG1 | 51/51 | 3/8 |
| 5D1 | IgG2b | 51/51 | 8/8 |
| 14D8 | IgG1 | 50/51 | 3/8 |
| 14D7 | IgG1 | 14/51 | 8/8 |
| 2F10 | IgG1 | 8/51 | 8/8 |
| Me-7 | IgG2a | 9/51 | 8/8 |
a
IgG, immunoglobulin G.
b
Reactivity was considered positive when the ODs were greater than twice the reading obtained for control wells without antibody.
c
N. meningitidis strains tested included two strains of serogroup B and one strain each of serogroups D, X, Z, A, Y, and W-135.