Figure 6.

There are no significant changes in Epidermal Growth Factor secretion between healthy and preeclamptic placentas treated with or without Rosiglitazone. Secretion of Epidermal Growth Factor (EGF) was measured via Luminex assay from conditioned media from non-treated control and preeclamptic (PE) placentas (A) and vehicle- or Rosiglitazone (Rosi)-treated PE placentas (B). There was no significant change in EGF secretion between PE and control placentas (A, n > 10) and between vehicle and Rosi-treated PE placentas in the PE compared to control placentas however this was not statistically significant (B, n = 14). (Protein secretion was measured by a Luminex assay where experimental values were determined relative to a standard curve. Statistical analysis was performed by student’s t-test to determine significant differences between groups, bar plots and data reported are reported as mean pg/mL values ± SEM).