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. 2022 Oct 23;11(21):3325. doi: 10.3390/foods11213325

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of dietary tannic acid on liver lipid accumulation, oxidative stress, liver toxicity and systemic inflammation in mice induced by high-fat diet. (A) Hepatic histopathologic appearance by Oil Red staining, (B) the concentration of TC and TG in the liver, (C) the content of MDA and SOD in the liver, (D) the content of ALT, AST and AKP in the liver, (E) the content of ALT and AST in serum, (F) the content of IgE, IgM, IgG and IgA in serum, (G) the content of LPS in serum, (H) the content of TNF-α and IL-6 in serum, liver, and colon, (I) hepatic histopathologic appearance by H&E staining. Black arrows indicate the inflammatory infiltration structure. Data are expressed as mean ± SEM. Different letters between any two groups indicated that there was significant difference between the two groups (p < 0.05).