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An alignment of the amino acid sequences of coronavirus spike proteins in the region of the S1/S2 junction, illustrating the sequence of SARS-CoV-2 (Wuhan-Hu-1) and some of its closest relatives. The FCS is indicated (PRRAR'SVAS), and furin cuts the spike protein between R and S, as indicated by the red arrowhead. Adapted from Chan and Zhan (4).
