Table 1.
Subjects characteristic by glucose tolerance status.
| Allsubjects | Obesity* | IFG | IGT | T2DM | p | R | |
|---|---|---|---|---|---|---|---|
| n (%) | 228 | 191 (83.77) | 7 (3.07) | 25 (10.96) | 5 (2.19) | ||
| Sex – Male, n (%) | 110 (48.25) | 99 (51.83) | 5 (71.43) | 11 (44) | 2 (40.00) | ||
| Sex – Female, n (%) | 118 (51.75) | 92 (48.17) | 2 (28.57) | 14 (56.00) | 3 (60.00) | ||
| Age (years) | 10.4 ± 3.6 | 10.4 ± 3.58 | 12.33 ± 2.78 | 10.88 ± 3.14 | 17.34 ± 0.53 | <0.0001 | 0.31 |
| Weight (kg) | 62.7 ± 23.9 | 60.10 ± 23.15 | 77.96 ± 16.28 | 71.73 ± 25.53 | 94.26 ± 13.78 | 0.0005 | 0.28 |
| Weight SD | 2.98 ± 0.91 | 2.96 ± 0.90 | 2.8 ± 0.92 | 3.23 ± 1.00 | 2.71 ± 0.99 | 0.4505 | 0.11 |
| Height (m) | 1.47 ± 0.19 | 1.45 ± 0.19 | 1.63 ± 0.10 | 1.54 ± 0.19 | 1.67 ± 0.06 | 0.0016 | 0.26 |
| Height SD | 1.33 ± 1.23 | 1.30 ± 1.18 | 1.77 ± 1.22 | 1.67 ± 1.48 | -0.07 ±1.29 | 0.0238 | 0.20 |
| BMI (kg/m2) | 27.83 ± 4.70 | 27.38 ± 4.34 | 29.92 ± 8.94 | 29.43 ± 4.74 | 33.84 ± 4.77 | 0.0023 | 0.25 |
| BMI SD | 2.98 ± 0.74 | 2.98 ± 0.74 | 2.65 ± 1.01 | 3.08 ± 0.72 | 2.82 ± 0.62 | 0.5621 | 0.10 |
| Fatty liver on ultrasound. n (%) | 51 (23.61) | 36 (19.57) | 3 (42.86) | 9 (40.91) | 3 (100) | ||
| ALT (U/l) | 25.9 ± 19.1 | 24.00 ± 15.41 | 22.83 ± 16.23 | 27.88 ± 12.79 | 85.80 ± 48.27 | <0.0001 | 0.51 |
| AST (U/l) | 26.3 ± 10.8 | 25.50 ± 9.19 | 20.50 ± 7.97 | 26.33 ± 8.41 | 58.00 ± 21.97 | <0.0001 | 0.48 |
| Cholesterol (mg/dl) | 166.8 ± 36.4 | 164.26 ± 34.48 | 164.29 ± 49.63 | 179.88 ± 37.67 | 207.00 ± 57.24 | 0.0177 | 0.21 |
| HDL-C (mg/dl) | 47.0 ± 14.5 | 47.25 ± 14.76 | 45.86 ± 7.95 | 47.91 ± 14.93 | 36.80 ± 5.22 | 0.4490 | 0.11 |
| LDL-C (mg/dl) | 101.5 ± 28.3 | 100.0 ± 27.27 | 98.14 ± 40.81 | 112.09 ± 31.10 | 111.40 ± 32.23 | 0.2195 | 0.14 |
| TG (mg/dl) | 105.9 ± 69.5 | 97.80 ± 50.34 | 142.57 ± 152.28 | 122.15 ± 54.71 | 284.00 ± 226.03 | <0.0001 | 0.42 |
| Glucose 0’ OGTT (mg/dl) | 86.0 ± 8.2 | 84.46 ± 7.25 | 104.39 ± 4.03 | 90.36 ± 7.00 | 97.14 ± 2.62 | <0.0001 | 0.51 |
| Insulin 0’ OGTT (μIu/ml) | 15.3 ± 11.9 | 13.74 ± 8.78 | 43.77 ± 39.56 | 17.43 ± 6.27 | 26.90 ± 2.02 | <0.0001 | 0.47 |
| Glucose 120’ OGTT (mg/dl) | 114.7 ± 27.2 | 106.13 ± 15.99 | 120.90 ± 11.59 | 150.17 ± 11.37 | 224.90 ± 20.11 | <0.0001 | 0.82 |
| Insulin 120’ OGTT (μIu/ml) | 91.4 ± 89.1 | 69.96 ± 52.61 | 121.21 ± 81.82 | 198.14 ± 148.11 | 262.56 ± 161.03 | <0.0001 | 0.56 |
| HOMA-IR | 3.36 ± 3.01 | 2.90 ± 1.94 | 11.53 ± 10.95 | 3.91 ± 1.56 | 6.44 ± 0.34 | <0.0001 | 0.52 |
| Quicki | 0.33 ± 0.03 | 0.34 ± 0.03 | 0.29 ± 0.04 | 0.32 ± 0.02 | 0.29 ± 0.00 | <0.0001 | 0.37 |
| Matsuda | 5.74 ± 4.06 | 6.43 ± 4.12 | 2.52 ± 1.68 | 2.76 ± 1.19 | 1.40 ± 0.35 | <0.0001 | 0.37 |
* Obesity, children with obesity with no carbohydrates metabolism disorders; BMI, body mass index; Glucose 0’ OGTT, fasting glucose; Insulin 0’ OGTT, fasting insulin; Glucose 120’ OGTT, glucose after 2 hours of oral glucose tolerance test; Insulin 120’ OGTT, insulin after 2 hours of oral glucose tolerance test.