TABLE 3.
Cost‐effectiveness study outcomes and WTP thresholds
| Study | Treatment | Location | ICER (Cost per QALY) | ICER (AUD per QALY) | QALY gained | Willingness to Pay Threshold (WTP) | WTP (AUD) a | CEAC probability |
|---|---|---|---|---|---|---|---|---|
| Roze et al. (2015) 12 | CSII only vs SAP | Sweden | SEK 545,005 | $99,942 | 0.760 | SEK 500,000 | $91,700 | N/A |
| Roze et al. (2016) 13 | CSII only vs. SAP | France | EUR 30,163 | $58,978 | 1.190 | EUR 30,000 | $58,700 |
Hyper: EUR 30,000–80% EUR 50,000–100% |
| EUR 22,005 | $43,027 | 1.440 |
Hypo: EUR 30,000–100% |
|||||
| Roze et al. (2016) 14 | CSII only vs. SAP | United Kingdom | EUR 12, 233 | $27,871 | 2.990 | GBP 20,000–30,000 | $45,600–$68,400 | GBP 20,000–100% |
| Roze et al. (2017) 15 | CSII only vs. SAP | Denmark | DKK 156,082 | $32,538 | 1.450 |
DKK 225,000 DKK 375,000 |
$46,900 –$78,200 |
Hyper: DKK 225,000–90% DKK 375,000 ‐ >99% |
| DKK 89,868 | $18,734 | 1.880 |
Hypo: DKK 225,000–100% |
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| Conget et al. (2018) 16 | CSII only vs. SAP | Spain | EUR 25,394 | $59,833 | 1.880 | EUR 30,000 | $70,700 | EUR 30,000–97.50% |
| Nicolucci et al. (2018) 17 | CSII only vs. SAP | Italy | EUR 44,982 | $93,772 | 1.448 | EUR 50,000 | $104,200 |
Hyper: EUR 50,000–69.2% EUR 84,000–100% |
| EUR 33,692 | $70,237 | 1.877 |
Hypo: EUR 36,000–68.1% EUR 62,000–100% |
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| Roze et al. (2019) 18 | CSII only vs. SAP | Turkey | TRY 76,971 | $65,144 | 1.400 | TRY 80,000 | $67,700 |
Hyper: TRY 80,000–64%, TRY 84,000–80% |
| TRY 69,534 | $58,850 | 1.730 |
Hypo: TRY 80,000–95% |
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| Chaugule et al. (2017) 19 | MDI for both | Canada | CAD 33,78 | $43,416 | 3.350 | CAD 50,000 | $64,200 | CAD 50,000–100% |
| Wan et al. (2018) 20 | MDI for both | United States of America | USD 98,108 | $149,634 | 0.540 | USD 100,000 | $152,500 | USD 100,000–90% |
| Roze et al. (2020) 21 | MDI for both | United Kingdom | Euro 9558 | $20,130 | 1.490 | GBP 20,000 | $42,100 | Base case: GBP 20, 000 ‐ ~99% |
| Euro 9, 478 | $19,961 | 1.390 | Hyper: GBP 20,000–98% | |||||
| Roze et al. (2021) 22 | MDI for both | Canada | CAD 16,931 | $20,188 | 2.090 | CAD 50,000 | $59,600 | CAD 50,000–100% |
| Kamble et al. (2012) 23 | MDI vs. SAP | United States of America | 3‐day sensor: USD 229,675 6‐day sensor: USD 168,104 | $386,667 $283,010 | 0.376 | USD 100,000 | $168,400 | N/A |
| Gomez et al. (2016) 24 | MDI vs. SAP | Colombia | USD 24, 000 | $37,188 | 3.810 | USD 26,750 | $42,500 | USD 26,750–99% |
| Jendle et al. (2019) 25 | CSII only vs. HCL | Sweden | SEK 164,236 | $27,731 | 1.900 | SEK 300,000 | $50,700 | SEK 97.60% |
| Pease et al. (2020) 26 | MDI vs. HCL | Australia | AUD 37,767 | $37,767 | 3.724 | AUD 50,000 | $50,000 | AUD 50,000–86% |
| Roze et al (2021) 27 | CSII only vs. HCL | UK | GBP 20,421 | $35,942 | 1.73 | GBP 30,000 | $62,000 | GBP 30,000–99.8% |
| Huang et al. (2010) 28 | (CSII 90% and MDI 10%) | United States of America | USD 98,679 | $172,852 | 0.60 | USD 100,000 | $175,200 | N/A |
| USD 78,943 | $138,281 | 1.11 | ||||||
| McQueen et al. (2011) 29 | CSII or MDI (varied) | United States of America | USD 45,033 | $77,269 | 0.523 | USD 100,000 | $171,600 | 70% |
| Garcia‐Lorenzo et al. (2018) 30 | CSII and MDI | Spain | EUR 2554723 | $6,019,360 | 0.046 | EUR 20,000 to 25,000 | $47,100–$58,900 | ~0% |
Abbreviations: CEAC, cost effectiveness acceptability curve.
a
WTP threshold rounded to the nearest hundred.