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. Author manuscript; available in PMC: 2023 Oct 18.
Published in final edited form as: Brain Behav Immun. 2022 May 14;104:18–28. doi: 10.1016/j.bbi.2022.05.007

Fig. 2.

Fig. 2.

T-lymphocyte TH knockout does not affect RSDS-induced anxiety-like or social behavior. Mice were tested for anxiety-like and pro-social behavior following control or RSDS paradigms. A) Left, Representation of elevated zero maze for anxiety-like behavior. Middle, Total distance moved on elevated zero maze, Two-way ANOVA results; stress p < 0.0001, genotype p = 0.3042, interaction p = 0.8672. Right, Time in open arm of elevated zero maze, Two-way ANOVA results; stress p = 0.0040, genotype p = 0.0575, interaction p = 0.4305. B) Left, Representation of social interaction test for social behavior. Right, Social interaction ratio (defined as time spent with CD-1 present/time spent with empty enclosure), Two-way ANOVA results; stress p = 0.0001, genotype p = 0.9233, interaction p = 0.9101. N = 15, 18, 11, 18 for respective genotypes and treatments in each panel. Two-way ANOVA Šidák multiple comparison tests of interest are listed if respective group or interaction effects were found to be significant.