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. 2022 May 14;92(6):1757–1766. doi: 10.1038/s41390-022-02104-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Infants not exposed (n = 140) and b exposed to antibiotics (n = 76). HAllA was used to determine pairwise associations that were statistically significant. Only species and antibiotic resistance genes with at least one statistically significant pairwise association were included in the plot. Dots represent statistically significant associations (Benjamini–Hochberg adjusted p value < 0.05). Due to length of gene-associated model names, ileS is used as an abbreviation for Bifidobacteria intrinsic ileS conferring resistance to mupirocin and rpoB is used for Bifidobacterium rpoB conferring resistance to rifampicin.