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. 2022 Oct 31;13:1049368. doi: 10.3389/fimmu.2022.1049368

Table 1.

Histopathological analysis of the effect of solnatide in mBSA arthritis.

Cell influx Synovial proliferation Cartilage damage Total Score
Naive 0 (0 -0) 0 (0-1) 0 (0-0) 0 (0-0)
NT 2.5 (2-3) 1 (1-2) 2 (2-3) 2.5 (2-3)
Solnatide 1 (1-2) 1 (0-1) 1 (1-2) 2.5 (1-2)
P value* 0.0086 0.0256 0.0208 0.0383

Mice subjected to mBSA arthritis received i.art. solnatide or saline (NT) 2 days after challenge with mBSA being sacrificed after 24h; a) Score (medians) of HE and Safranin-O stained whole joints compared using Mann-Whitney; n=6 animals/group; NT, non-treated; p value comparing NT vs Solnatide.