Table 1.
Cell influx | Synovial proliferation | Cartilage damage | Total Score | |
---|---|---|---|---|
Naive | 0 (0 -0) | 0 (0-1) | 0 (0-0) | 0 (0-0) |
NT | 2.5 (2-3) | 1 (1-2) | 2 (2-3) | 2.5 (2-3) |
Solnatide | 1 (1-2) | 1 (0-1) | 1 (1-2) | 2.5 (1-2) |
P value* | 0.0086 | 0.0256 | 0.0208 | 0.0383 |
Mice subjected to mBSA arthritis received i.art. solnatide or saline (NT) 2 days after challenge with mBSA being sacrificed after 24h; a) Score (medians) of HE and Safranin-O stained whole joints compared using Mann-Whitney; n=6 animals/group; NT, non-treated; p value comparing NT vs Solnatide.