TABLE 7.

Experimental data (Kampourakis et al., 2018) and hiMCE results due to the effect of 1 µM OM and 5 µM BLEB. pCa₅₀ represents the -log of the Ca²⁺ concentration associated with 50% of maximum tension. cTnC-E: data from cardiac troponin C (cTnC) E-helix obtained by a rhodamine probe. cRLC-E: Data from a probe connected to the myosin regulatory light chain (RLC).

#	Item	Kampourakis et al., 2018	Hi-MCE model (%)
1	Increase in pCa50 due to 1 µM OM	5.4–6.9% (cRLC-E)	5.8
		3.8–6.4% (cTnC-E)
2	Decrease in pCa50 due to 5 µM BLEB	2.1–5.5% (cRLC-E)	4.8
		2.6–5.7% (cTnC-E)
3	Reduction of Hill coef. Due to 1 µM OM	53.2–64.5% (cRLC-E)	58.9
		57.1–68.1% (cTnC-E)
4	Reduction of Hill coef. Due to 5 µM BLEB	59.5–73.5% (cRLC-E)	49.9
		44.8–58.3% (cTnC-E)
5	Reduction in max tension due to 1 µM OM	0–29% (cRLC-E)	25.3
		18–47% (cTnC-E)
6	Reduction in max tension due to 5 µM BLEB	66–90% (cRLC-E)	76.4
		64–80% (cTnC-E)