TABLE 3.
G1 | G2 | G3 | G4 | |
CONGA1180 | 2.0 (0.4)b | 1.3 (0.4)c | 2.7 (0.6)a | 2.8 (0.5)a |
iAUC60–180% | 36.6 (9.1)c | 47.0 (8.4)ab | 39.8 (10.5)bc | 51.6 (5.5)a |
iAUC180 | 268.8 (49.4)c | 242.5 (51.9)c | 330.0 (72.5)b | 442.9 (71.7)a |
NAUC180 | –25.5 (23.4)b | –2.2 (10.7)a | –57.8 (32.0)c | –8.0 (18.3)a |
Peak180 | 4.1 (0.6)b | 3.2 (0.5)c | 4.7 (0.7)a | 5.1 (0.8)a |
Nadir180 | –1.0 (0.4)a | –0.2 (0.7)a | –1.6 (0.4)b | –0.7 (0.8)a |
SD180 | 1.7 (0.2)c | 1.2 (0.2)d | 2.2 (0.3)a | 2.0 (0.4)b |
Values are mean (SD), except that NAUC120 is median (first quartile, third quartile). a, b, c, d, used for comparison between groups (P < 0.05).