Table 1.
Characteristics of included studies.
| Study | Country | Year of publication | Study design | Diagnostic criteria | Total population | Sample size |
|---|---|---|---|---|---|---|
| PCOS preceding | HT diagnosis | cases; controls | cases; controls | |||
| Petrikova (14) | Slovak Republic | 2015 | Cross section | Rotterdam | 64 cases; 68 controls | 12 cases; 7 controls |
| Janssen (15) | Germany | 2004 | Cohort | non- | 175 cases; 168 controls | 47 cases; 14 controls |
| Kachuei (16) | Iran | 2012 | Case-control | Rotterdam | 72 cases; 90 controls | 22 cases; 25controls |
| Petríková (17) | Slovenska Republika | 2012 | Cross section | Rotterdam | 64 cases; 68controls | 12 cases; 7 controls |
| Sinha (18) | India | 2013 | Cross section | Rotterdam | 80 cases; 80 controls | 18 cases; 1 controls |
| Garelli (19) | Italy | 2013 | Cross section | Rotterdam | 113 cases; 100 controls | 30 cases; 8 controls |
| Novais (20) | Brazil | 2015 | Cross section | Rotterdam | 65 cases; 65 controls | 28 cases; 17 controls |
| Duran (21) | Turkey | 2015 | Cross section | Rotterdam | 73 cases; 60 controls | 23 cases; 14 controls |
| Arduc (22) | Turkey | 2015 | Cross section | Rotterdam | 86 cases; 60 controls | 19 cases; 3 controls |
| Calvar (23) | Argentina | 2015 | Case-control | Rotterdam | 142 cases; 52 controls | 27 cases; 7 controls |
| Yu (24) | China | 2016 | Case-control | Rotterdam | 100 cases; 100 controls | 25 cases; 2 controls |
| Yasar (25) | Turkey | 2016 | Case-control | Rotterdam | 217 cases; 131 controls | 47 cases; 23 controls |
| Arora (26) | India | 2016 | Cross section | Rotterdam | 55 cases; 51 controls | 21 cases; 8 controls |
| Adamska (27) | Poland | 2020 | Cross section | Rotterdam | A:67,B:30,C:28,D:16 141 cases; 88 controls | 31 cases; 21 controls |
| Kim (28) | Korea | 2022 | Cross section | Rotterdam | 104 cases; 238 controls | 5 cases; 18 controls |
| Skrzynska (29) | Poland | 2022 | Cross section | non- | 80 cases; 64 controls | 18 cases; 9 controls |
| Al-Saab (30) | Syria | 2014 | Case-control | Rotterdam | 56 cases; 30 controls | 11 cases; 1 controls |
| Karaköse (31) | Turkey | 2017 | Cross section | Rotterdam | 97 cases; 71 controls | 39 cases; 11 controls |
| HT preceding PCOS diagnosis | cases; controls | cases; controls | ||||
| Ganie (32) | India | 2010 | Case-control | Rotterdam | 175 cases; 46 controls | 82 cases; 20 controls |
| Ho (33) | China | 2020 | Case-control | NR | 1332cases; 2664 controls | 19 cases; 16 controls |