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. 2022 Oct 31;9:870391. doi: 10.3389/fmed.2022.870391

TABLE 4.

Dry eye disease (DED)-related parameters in good and poor sleep groups of OSA cases and relevant controls.

Control
OSA
Good sleep (n = 67) Poor sleep (n = 58) P Good sleep (n = 45) Poor sleep (n = 80) P
DED (n, %) 31 (46.3) 22 (37.9) 0.370 17 (37.8) 54 (67.5) 0.002
Schirmer I test
(mm/5 min)
15.69 ± 6.97 15.52 ± 6.36 0.889 15.81 ± 5.34 15.72 ± 7.52 0.001
Oxford corneal staining score 0.76 ± 0.95 0.62 ± 1.08 0.444 0.09 ± 0.29 0.43 ± 0.85 <0.001
OSDI 15.71 ± 9.16 16.16 ± 11.05 0.806 12.31 ± 6.41 19.13 ± 14.36 <0.001
f-NITBUT (s) 7.29 ± 2.44 7.32 ± 2.32 0.948 7.87 ± 1.14 6.53 ± 2.00 <0.001
av-NITBUT (s) 10.31 ± 3.03 10.83 ± 3.06 0.342 11.11 ± 1.31 9.87 ± 2.31 <0.001
TMH (mm) 0.37 ± 0.07 0.39 ± 0.06 0.320 0.42 ± 0.05 0.37 ± 0.07 <0.001
Loss on upper eyelid meibography (%) 18.00 ± 8.44 17.62 ± 8.43 0.804 15.28 ± 3.03 21.24 ± 9.55 <0.001
Loss on lower eyelid meibography (%) 19.32 ± 8.25 19.70 ± 8.80 0.806 17.09 ± 3.80 21.96 ± 8.90 <0.001

Comparison among groups was calculated using unpaired t-test and chi-square exact test. The comparisons with statistical differences were marked in bold.