Table 2. Predictor screening for the survival of CC patients.
| Variables | Univariable Cox regression model | Multivariate Cox regression model | |||
|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | ||
| Age | 1.032 (1.031, 1.033) | <0.001 | 1.043 (1.041, 1.044) | <0.001 | |
| Gender | |||||
| Male | Ref | Ref | |||
| Female | 0.965 (0.938, 0.992) | 0.011 | 0.834 (0.810, 0.859) | <0.001 | |
| Race | |||||
| White | Ref | Ref | |||
| Black | 1.059 (1.015, 1.105) | 0.008 | 1.090 (1.044, 1.138) | <0.001 | |
| Others | 0.822 (0.779, 0.869) | <0.001 | 0.837 (0.792, 0.884) | <0.001 | |
| Marital status | |||||
| Married | Ref | Ref | |||
| Divorced | 1.251 (1.192, 1.312) | <0.001 | 1.219 (1.162, 1.280) | <0.001 | |
| Separated | 1.024 (0.887, 1.183) | 0.744 | 1.065 (0.921, 1.231) | 0.394 | |
| Single | 1.216 (1.168, 1.266) | <0.001 | 1.332 (1.277, 1.389) | <0.001 | |
| Unmarried or domestic partner | 0.953 (0.680, 1.334) | 0.779 | 1.273 (0.909, 1.783) | 0.160 | |
| Widowed | 1.800 (1.740, 1.864) | <0.001 | 1.261 (1.213, 1.311) | <0.001 | |
| Insurance status | |||||
| Insured | Ref | Ref | |||
| Insurance status unknown | 1.248 (1.203, 1.294) | <0.001 | 1.091 (1.052, 1.132) | <0.001 | |
| Any Medicaid | 1.366 (1.311, 1.423) | <0.001 | 1.377 (1.319, 1.437) | <0.001 | |
| Uninsured | 1.109 (1.020, 1.205) | 0.015 | 1.451 (1.331, 1.580) | <0.001 | |
| Tumor grade | |||||
| I | Ref | Ref | |||
| II | 1.497 (1.414, 1.585) | <0.001 | 1.225 (1.156, 1.298) | <0.001 | |
| III | 2.597 (2.442, 2.762) | <0.001 | 1.561 (1.465, 1.664) | <0.001 | |
| IV | 2.966 (2.739, 3.212) | <0.001 | 1.795 (1.654, 1.947) | <0.001 | |
| T stage | |||||
| T1 | Ref | Ref | |||
| T2 | 0.845 (0.793, 0.901) | <0.001 | 0.954 (0.893, 1.019) | 0.163 | |
| T3 | 1.480 (1.414, 1.550) | <0.001 | 1.269 (1.205, 1.336) | <0.001 | |
| T4 | 3.225 (3.072, 3.386) | <0.001 | 1.974 (1.868, 2.086) | <0.001 | |
| N stage | |||||
| N0 | Ref | Ref | |||
| N1 | 1.686 (1.630, 1.743) | <0.001 | 1.397 (1.348, 1.447) | <0.001 | |
| N2 | 2.972 (2.872, 3.076) | <0.001 | 2.151 (2.066, 2.239) | <0.001 | |
| M stage | |||||
| M0 | Ref | Ref | |||
| M1 | 4.445 (4.313, 4.581) | <0.001 | 3.106 (2.998, 3.219) | <0.001 | |
| Surgery | |||||
| Yes | Ref | Ref | |||
| No | 5.286 (5.019, 5.567) | <0.001 | 2.930 (2.753, 3.119) | <0.001 | |
| Radiotherapy | |||||
| Yes | Ref | ||||
| No | 0.691 (0.631, 0.757) | <0.001 | |||
| Nodes examined | 0.976 (0.975, 0.978) | <0.001 | 0.982 (0.981, 0.984) | <0.001 | |
CC, colon cancer; HR, hazard ratio; CI, confidence interval; ref: reference.