Table 3. Standardized associations between the plasma levels of CEA, CA199, and Hsp90α (per SD) and liver metastasis in CRC.
| Variable | Univariable | Multivariable | |||
|---|---|---|---|---|---|
| OR (95% CI) (N=439) | P value | OR (95% CI)* (N=439) | P value | ||
| CEA | 7.82 (3.75, 16.31)# | <0.001# | 2.72 (1.49, 4.98)# | 0.001# | |
| CA199 | 2.98 (1.93, 4.60)# | <0.001# | 1.60 (1.14, 2.25)# | 0.006# | |
| Hsp90α | 1.31 (1.08, 1.58)# | 0.005# | 1.36 (1.03, 1.80)# | 0.03# | |
The odds ratio (OR) is shown for 1 standard deviation increment in each plasma biomarker. *, adjustment for age, sex, and stage; #, indicates a statistically significant result. CA199, carbohydrate antigen199; CRC, colorectal cancer; CEA, carcinoembryonic antigen; CI, confidence interval; Hsp90α, heat shock protein 90 alpha.