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. 2022 Nov 14;32(1):228–243. doi: 10.1007/s00586-022-07444-z

Table 7.

Prognostic factors of survival in the univariate and multivariate analysis

Author Univariate analysis Multivariate analysis
Lei M Preoperative ambulatory status, targeted therapy, preoperative ECOG PS, number of involved vertebrae, visceral metastases, time developing neurologic deficits Preoperative ambulatory status, targeted therapy, number of involved vertebrae, visceral metastasis, time developing neurologicr deficits
Chen YJ Histology of primary tumor, preoperative Karnofsky PS, postoperative Frankel grade Preoperative Karnofsky PS
Park SJ Time developing neurologic deficits, responsiveness to preoperative chemotherapy, postoperative chemotherapy, postoperative ECOG PS, postoperative ambulatory status Time developing neurologic deficits, postoperative chemotherapy, postoperative ECOG PS
Zairi F Preoperative Karnofsky PS, preoperative Frankel grade, the delay between the cancer diagnosis and the occurrence of spine metastases
Tang Y Bisphosphonate treatment, radiotherapy, targted therapy, postoperative Frankel grade Radiotherapy, targted therapy, postoperative Frankel grade
Chen Q Age, extraspinal bone metastasis foci, visceral metastasis, preoperative Frankel grade, targeted therapy, radiotherapy Age, extraspinal bone metastasis foci, visceral metastasis, preoperative Frankel grade, chemotherapy, targeted therapy
Truong VT Tobacco use, preoperative and postoperative ASIA score, postoperative ambulatory status, postoperative radiotherapy, and postoperative chemotherapy Tobacco use, postoperative ambulatory status, postoperative radiotherapy, and postoperative chemotherapy
Tancioni F Control of the primary tumor, the delay between the cancer diagnosis and the occurrence of spine metastases, visceral metastases, number of involved vertebrae, extraspinal bone metastasis foci
Jung JM Charlson comorbidity index, number of involved vertebrae

ECOG Eastern Cooperative Oncology Group, PS performance status, ASIA American Spinal Injury Association